Bioactive secondary metabolites from marine actinomycetes and their inhibitory effect on bacteria of Drinking water

Document Type : Original Article

Authors

1 Microbial Biotechnology Department, National Research Centre, El- Buhouth Street, Dokki, Cairo, Egypt.

2 Microbiology Department, Faculty of Science, Benha University, Benha, Egypt.

3 Microbial Chemistry Department, National Research Centre, El-Buhouth Street, Dokki, Cairo, Egypt.

Abstract

This study focuses on the isolation of marine actinomycetes, their cultivation through
fermentation on rice medium, and the subsequent evaluation of their antimicrobial
activity. Marine environments are known to harbor diverse and potentially valuable
microorganisms, including actinomycetes, which are renowned for their capacity to
produce bioactive compounds.
Marine actinomycetes were isolated from marine samples, and their cultivation was
carried out using a rice-based medium. This fermentation process aimed to stimulate the
production of biologically active secondary metabolites. These metabolites are of
Journal of Basic and Environmental Sciences 11 (2024) 60-70
-61-
particular interest due to their potential antimicrobial properties, which could have
significant applications in the field of medicine and biotechnology.
The isolated actinomycetes' rice medium extracts were carefully examined for their
antimicrobial activity. The study assessed their effectiveness in inhibiting the growth of
various microorganisms, highlighting their potential as a source of novel bioactive
compounds with applications in the field of antimicrobial agents. The results of this
investigation contribute to our understanding of the bioresources present in marine
ecosystems and their potential for developing new therapeutic agents.

Keywords

Journal of Basic and Environmental Sciences
Volume 11, Issue 1
January 2024
Pages 60-70

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