Metal complexes of Schiff base: Preparation, Characterization and Antimicrobial activity

Mahmoud, Walaa H.; Abd EL-Fatah, Noha E.; EL -Dessouk, Maher M.I.; Mohamed, Gehad G.

doi:10.21608/jbes.2019.371101

Metal complexes of Schiff base: Preparation, Characterization and Antimicrobial activity

Document Type : Original Article

Authors

¹ Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt

² Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt Egypt Nanotechnology Center, Cairo University, El-Sheikh Zayed, 6th October City, Giza 12588, Egypt

10.21608/jbes.2019.371101

Abstract

The tridentate (HL) Schiff base was synthesized by reacting 2-quinolinecarboxaldehyde with 3-aminophenol in absolute
ethanol. The resulting HL ligand was also coordinated with the Ni(II) and Cd(II) ions. This Schiff base and its Ni(II) and
Cd(II) complexes were characterized by multiple and usual methods including the 1H NMR, elemental analysis, FT-IR,
UV-Vis, and magnetic moments. It was found that the ligand acts as a tridentate chelate. Both compounds, HL ligand and
its Ni(II), Cd(II) complexes were as well tested in biological activity. The obtained results indicate that the Ni(II)
complex only exhibit antifungal activity and the two complexes have antibacterial activity towards the same organism
studied.

Keywords