99Mo/99mTc radioisotope generator based on adsorption of 99Mo (VI) onto zirconium selenomolybdate as column matrix

Document Type : Original Article

Authors

1 Radioactive Isotopes department, Hot Labs. Center Atomic Energy Authority, P.O.Box 13759, Cairo, Egypt.

2 Chemistry Department, Faculty of Science, Damietta University.

Abstract

Zirconium selenomolybdate99Mo gel was prepared by adsorption of 99Mo onto inactive zirconium selenomolybdate
gel matrix. The batch equilibration method was used for investigation of the interaction between 99Mo (VI) radionuclide
and the zirconium selenomolybdate gel matrix in HCl acid solutions. The apparent capacity of zirconium
selenomolybdate for 99Mo(VI) was determined by dynamic method and was found to be 0.13 mmol/g.
99Mo/99mTc
radioisotope generators of the elution mode was prepared based on adsorption of 99Mo radiotracer, of low specific
activity, onto chromatographic columns packed with 2g zirconium selenomolybdate gel matrix. The radioactivity of
99mTc was eluted with 0.9% NaCl solution each 24 h at a flow rate 0.5 ml/min. The eluted 99mTc radioactivity was of high
yield and quality over the period of investigation