Phthalate Ester Derivative Isolated from The Coral Associated Fungus “Aspergillus Sp. 2c1-Egy”

Khalil, A.A.; Aly, A.A.; Donia, S.G.; Ibrahim, Amal M.; Abd El-Hady, Faten K.; AbdelAziz, Mohamed S.; Shaker, Kamel H.

doi:10.21608/jbes.2019.370574

Phthalate Ester Derivative Isolated from The Coral Associated Fungus “Aspergillus Sp. 2c1-Egy”

Document Type : Original Article

Authors

¹ Chemistry Department, Faculty of Science, Benha University

² Chemistry of Natural Products Department, National Research Center, Egypt.

³ Department of Microbial Chemistry, National Research Center, Egypt.

⁴ Chemistry of Natural Compounds Department, National Research Center, Egypt.

10.21608/jbes.2019.370574

Abstract

The culture of the fungus Aspergillus sp. 2C1-EGY was isolated from the soft coral; Lobophyton sp. the fungus was
extracted with organic solvents. The combined crude extracts were subjected to silica gel column, and final purification
by Crystillization which successively led to the isolation, structural elucidation and biological activities of the compound
1. The structure of the compound 1 was determined on the basis of NMR and mass spectral data analysis, as well as
comparison of their NMR data with those in the literature. antioxidant activity with DPPH radical scavenging activity
and Acetylcholinesterase (AChE) inhibitory activity were evaluated Coral Associated fungus; Aspergillus sp. 2C1-EGY, phthalate ester, Biological Activity.

Keywords